Mark Siegal Publications

Levy SF, Siegal ML. 2008. Network hubs buffer environmental variation in Saccharomyces cerevisiae. PLoS Biology, in press.


Siegal ML, Promislow DEL, Bergman A. 2007. Functional and evolutionary inference in gene networks: does topology matter? Genetica 129:83-103. [pdf]


Siegal ML, Bergman A. 2006. Canalization, pp. 235-251 in Evolutionary Genetics: Concepts and Case Studies, Fox CW and Wolf JB, eds. New York: Oxford University Press. [link]


Siegal ML, Baker BS. 2005. Functional conservation and divergence of intersex, a gene required for female differentiation in Drosophila melanogaster. Dev Genes Evol 215:1-12. [pdf]


Arbeitman MN, Fleming AA, Siegal ML, Null BH, Baker BS. 2004. A genomic analysis of Drosophila somatic sexual differentiation and its regulation. Development 131:2007-2021. [pdf]


Bergman A, Siegal ML. 2003. Evolutionary capacitance as a general feature of complex gene networks. Nature 424:549-552. [pdf] [news and views pdf]


Garrett-Engele CM, Siegal ML, Manoli DS, Williams BC, Li H, Baker BS. 2002. intersex, a gene required for female sexual development in Drosophila, is expressed in both sexes and functions together with doublesex to regulate terminal differentiation. Development 129:4661-4675. [pdf]


Siegal ML, Bergman A. 2002. Waddington's canalization revisited: developmental stability and evolution. Proc Natl Acad Sci USA 99:10528-10532. [pdf] [commentary pdf]


Marín I, Siegal ML, Baker BS. 2000. The evolution of dosage-compensation mechanisms. BioEssays 22:1106-1114. [pdf]


Siegal ML, Hartl DL. 2000. Application of Cre/loxP in Drosophila. Site-specific recombination and transgene coplacement. Methods Mol Biol 136:487-495. [pdf]


Siegal ML, Hartl DL. 1999. Oviposition-site preference in Drosophila following interspecific gene transfer of the Alcohol dehydrogenase locus. Behav Genet 29:199-204. [pdf]


Siegal ML, Hartl DL. 1998. An experimental test for lineage-specific position effects on alcohol dehydrogenase (Adh) genes in Drosophila. Proc Natl Acad Sci USA 95:15513-15518. [pdf]


Siegal ML, Hartl DL. 1996. Transgene coplacement and high efficiency site-specific recombination with the Cre/loxP system in Drosophila. Genetics 144:715-726. [pdf]


Siegal ML, Petrov DA, De Aguiar D. 1996. Triple-ligation strategy with advantages over directional cloning. BioTechniques 21:614-619. [pdf]